GrayMatters Health Ltd. – Co-Founders Shai Attia, VP R&D, Oded Kraft, CEO and Rani Cohen, Executive chairman, BD – Location(s): Haifa, Israel

GrayMatters Health Ltd., based in Haifa, Israel, is developing innovative neuroscience-based digital therapeutics for mental health disorders therapy, initially focusing on PTSD therapy. GrayMatters Health’s product is using an amygdala-fMRI-guided machine learning model for processing EEG signals to train patients with PTSD how to down regulate specific brain activity, associated with PTSD. The company’s investigational device, Prism for PTSD, is currently undergoing clinical studies, and will be submitted for FDA review in the future. The company was founded by three experienced entrepreneurs who licensed the core technology, developed by Prof. Hendler, from Tel Aviv Sourasky Medical Center and Tel Aviv University in Israel.

Kraft added, “We are excited with the opportunity to be working with BTA and the HITLAB ecosystem on introducing Prism for PTSD to the US healthcare system, be it through pilots or other collaborations.”

HITLAB Breakthrough Alliance Director, Dr. Sara Chokshi spoke about how digital health innovation is increasing worldwide, resulting in growing importance of rapidly testing and verifying value for aiding development and scaling of these promising solutions. “Healthcare is buzzing with digital innovation which is amazing. The next step is to turn to real-world evidence generation to demonstrate that solutions are indeed effective and that they can work within existing systems,” Dr. Chokshi added.

The HITLAB Breakthrough Alliance – having evolved from the Digital Health Breakthrough Network partnership between the NYC Economic Development Corporation (NYCEDC) and HITLAB – is now working with the fifth group of startup solutions selected to be verified by HITLAB and strategic partners.

To join the HITLAB Breakthrough Alliance as a member or apply as an innovator for the next class, please visit www.hitlab.org/breakthrough.